Fibroblast growth factor 5

Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5

T. Wang, Zhang, Y., Wang, H. D., Shen, Y., Liu, N., Cao, J., Yu, X. J., Dong, C. S., and He, X. Y., Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5, vol. 14, pp. 13754-13763, 2015.

MicroRNAs are very small endogenous RNA molecules that play a crucial role in an array of biological processes, including regulation of skin morphogenesis. The microRNA let-7b is thought to modulate animal hair growth, by binding target genes that encode growth factors. Fibroblast growth factor 5 (FGF5) has been previously reported to be involved in the initiation of the catagen phase of hair growth.

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