Familial hypercholesterolemia

Prediction of genetic risk factors of atherosclerosis using various bioinformatic tools

H. X. Wang, Zhao, Y. X., Wang, H. X., Zhao, Y. X., Wang, H. X., and Zhao, Y. X., Prediction of genetic risk factors of atherosclerosis using various bioinformatic tools, vol. 15, p. -, 2016.

The aim of this study was to identify potential markers of atherosclerosis development in familial hypercholesterolemia (FH) patients. GSE13985 microarray data, generated using blood samples from 5 FH patients and 5 matched controls, was downloaded from the Gene Expression Omnibus. Differentially expressed genes (DEGs) between FH and controls were identified and a protein-protein interaction (PPI) network was constructed. Module and hub proteins were screened in this network.

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