Exfoliated cells

Increased micronucleus frequency in exfoliated cells of the buccal mucosa in hairdressers

L. N. Rickes, Alvarengo, M. C., Souza, T. M., Garcias, G. L., and Martino-Roth, M. G., Increased micronucleus frequency in exfoliated cells of the buccal mucosa in hairdressers, vol. 9, pp. 1921-1928, 2010.

Hairdressers are exposed daily to chemical substances, such as dyes, chemical straighteners and curling chemicals, which can be absorbed, inhaled or possibly ingested. We analyzed the frequency of micronuclei (MNC) in exfoliated cells of the buccal mucosa of 50 hairdressers and 50 controls in Pelotas, RS, Brazil. An assessment was carried out on the incidence of MNC, binucleated cells (BNC), broken egg cells (BEC), budding cells (BC), and the sum of anomalies (SA), in 2000 cells per individual. The data were analyzed with SPSS, using the Mann-Whitney U-test, α = 0.05.

Micronucleus test on gas station attendants

C. Iribarrem Benites, Amado, L. Lund, Vianna, R. Aloma Pack, and Martino-Roth, Mda Graça, Micronucleus test on gas station attendants, vol. 5, pp. 45-54, 2006.

In the present study, the micronucleus test was applied in exfoliated cells of buccal mucosa to assess the mutagenicity risk associated with occupational exposure for gas station attendants. For each individual, 2000 exfoliated buccal cells were analyzed for micronucleus frequency. A highly significant difference was found between exposed and control groups. Likewise, a significant difference was found between these groups regarding the frequency of binucleated and broken egg cells.

Subscribe to Exfoliated cells