Esophageal cancer

Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis

J. Z. Peng, Xue, L., Liu, D. G., and Lin, Y. H., Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis, vol. 14, pp. 9024-9033, 2015.

Although many epidemiologic studies have investigated the p53 codon 72 polymorphism and its association with esophageal cancer (EC) in China, definite conclusions could not be drawn. To clarify the effects of p53 codon 72 polymorphism on the risk of EC, we performed a meta-analysis on the Chinese population. A total of 13 studies including 3308 patients and 5115 controls were involved in this meta-analysis.

Characterization and effects of miR-21 expression in esophageal cancer

S. - W. Wen, Zhang, Y. - F., Li1, Y., Liu, Z. - X., Lv, H. - L., Li, Z. - H., Xu, Y. - Z., Zhu, Y. - G., and Tian, Z. - Q., Characterization and effects of miR-21 expression in esophageal cancer, vol. 14, pp. 8810-8818, 2015.

The aim of this study was to investigate the expression of miR-21 in esophageal cancer and the impact of miR-21 on apoptosis, invasion, and the expression of target genes in esophageal cancer cells. Fluorescence quantitative polymerase chain reaction analysis was used to detect the expression of miR-21 in human esophageal tissues, adjacent tissues, and an esophageal cancer cell line (TE-13). The antisense miR-21 oligonucleotide was generated commercially using the solid-phase chemical synthesis method.

Subscribe to Esophageal cancer