Epstein-Barr virus-positive nasopharyngeal carcinoma

Integrated miRNA-mRNA analysis of Epstein-Barr virus-positive nasopharyngeal carcinoma

L. H. Zhu, Miao, X. T., and Wang, N. Y., Integrated miRNA-mRNA analysis of Epstein-Barr virus-positive nasopharyngeal carcinoma, vol. 14, pp. 6028-6036, 2015.

This study aims to identify the crucial miRNAs in Epstein-Barr virus-positive nasopharyngeal carcinoma (NPC) and their target genes. Gene expression profile data (GSE12452) that included 31 NPC and 10 normal nasopharyngeal tissue specimens were downloaded. Differentially expressed genes (DEGs) were identified using significance analysis of microarrays. The underlying function of DEGs was predicted via Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses.

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