Screening and functional microarray analysis of differentially expressed genes related to osteoporosis
, “Screening and functional microarray analysis of differentially expressed genes related to osteoporosis”, vol. 13, pp. 3228-3236, 2014.
We searched for key genes that could accurately predict bone mineral density. The gene expression profile GSE7429 was downloaded from the Gene Expression Omnibus database, which includes 20 samples, 10 with high and 10 with low bone mineral density. The differentially expressed genes (DEGs) were identified with packages in R language. Further, BLASTX was used to obtain COG function classifications of all the DEGs. The GOTM software was used to find DEGs enriched modules. The functions of genes in the modules was also predicted with the software GENECODIS.
