Empirical Bayesian model

Construction of a gene-gene interaction network with a combined score across multiple approaches

A. M. Zhang, Song, H., Shen, Y. H., and Liu, Y., Construction of a gene-gene interaction network with a combined score across multiple approaches, vol. 14, pp. 7018-7030, 2015.

Recent progress in computational methods for inves­tigating physical and functional gene interactions has provided new insights into the complexity of biological processes. An essential part of these methods is presented visually in the form of gene interaction networks that can be valuable in exploring the mechanisms of disease. Here, a combined network based on gene pairs with an extra layer of re­liability was constructed after converting and combining the gene pair scores using a novel algorithm across multiple approaches.

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