Elderly

Effects of intravenous analgesia with combined dezocine and butorphanol on postoperative cognitive function in elderly patients

B. X. Ren, Zong, J., Tang, J. C., Sun, D. P., Hui, X., Li, R. Q., Zhang, J. L., and Ji, Y., Effects of intravenous analgesia with combined dezocine and butorphanol on postoperative cognitive function in elderly patients, vol. 14, pp. 5571-5576, 2015.

The aim of this study was to observe the analgesic effects of the combination of dezocine and butorphanol on postoperative cognitive function in elderly patients. Forty elderly patients undergoing upper abdominal surgeries or thoracotomies with general anesthesia were randomly divided into the dezocine and butorphanol group or the butorphanol group (20 patients per group). A visual analog scale was used to evaluate analgesia and the degree of malignant vomiting. The Ramsay scoring method was used to evaluate sedation.

Outcomes of laryngectomy in elderly patients with laryngeal carcinoma

R. J. Shi, Xu, C. Z., Zhang, C. P., Jiang, C. Y., Sun, Y. Y., Yan, X. J., and Wang, P. H., Outcomes of laryngectomy in elderly patients with laryngeal carcinoma, vol. 13, pp. 1955-1963, 2014.

Laryngeal carcinoma is a common tumor of the head and neck region. This study aimed to examine the outcomes of laryngectomy in elderly patients with laryngeal carcinoma. One-hundred twenty-two patients (male, 117; female, 5) aged 60 years or older (range, 60-94 years) who underwent laryngectomy between 1996 and 2010 were included. All patients were diagnosed with squamous cell carcinoma of the larynx, and 95 patients (77.9%) had additional concurrent diseases.

Reason and treatment of failure of proximal femoral nail antirotation internal fixation for femoral intertrochanteric fractures of senile patients

J. J. Liu, Wang, J. G., Shan, L. C., Deng, B. Y., Zhu, W., and Cai, Z. D., Reason and treatment of failure of proximal femoral nail antirotation internal fixation for femoral intertrochanteric fractures of senile patients, vol. 13, pp. 5949-5956, 2014.

The cause of postoperative failure after the treatment of femoral intertrochanteric fracture with proximal femoral nail antirotation (PFNA) was analyzed, and the reoperative methods were examined. Nine failures of 308 femoral intertrochanteric fracture patients with PFNA were treated with femoral prosthesis total hip replacement (THR) and reoperative internal fixation. All nine patients were analyzed to determine the cause of failure.

Effects of rehabilitation management on gastric emptying function in older adults with diabetes

Z. M. Shao, Yao, J. F., Chen, J., Yu, Z. W., Yu, X. F., Zheng, J. J., and Tang, X., Effects of rehabilitation management on gastric emptying function in older adults with diabetes, vol. 13, pp. 9244-9252, 2014.

The relationship between gastric emptying dysfunction and blood glucose concentration in elderly with type 2 diabetes mellitus was investigated, and the effect of rehabilitation exercise prescription training on gastric emptying in the geriatric diabetic patients was evaluated. A total of 160 older type 2 diabetic adults and 30 cases of non-diabetic patients were studied with regard to the gastric half emptying time (GET1/2) of solid meals radiolabelled with 99mTc.

Prevalence of variants that confer risk for venous thromboembolism in an elderly population of northeastern Brazil

H. Ferreira-Fernandes, Costa, P. N., Fernandes, H. F., Araújo-Neto, A. P., Motta, F. J., Canalle, R., Yoshioka, F. K., Guerreiro, J. F., Burbano, R. R., Rey, J. A., and Pinto, G. R., Prevalence of variants that confer risk for venous thromboembolism in an elderly population of northeastern Brazil, vol. 12, pp. 3698-3707, 2013.

Venous thromboembolism (VTE) is an important cause of morbidity and mortality stemming from cardiovascular disease. It is a multifactorial disease caused by a combination of acquired risk factors, of which advanced age is the most significant, and genetic factors, including the variants FV G1691A, FII G20210A, and MTHFR C677T. We estimated the prevalence of these genomic variants in an elderly population of northeastern Brazil. The study included 188 elderly persons (65-93 years), of which 68 (36.2%) were men and 120 (63.8%) were women.

Association of lipase lipoprotein polymorphisms with high-density lipoprotein and triglycerides in elderly men

L. M. Q. Araújo, Cendoroglo, M. S., Gigek, C. O., Chen, E. S., and M. Smith, deA. C., Association of lipase lipoprotein polymorphisms with high-density lipoprotein and triglycerides in elderly men, vol. 9, pp. 89-96, 2010.

Lipoprotein lipase is essential for triglyceride hydrolysis. The polymorphisms S447X in exon 9 and HindIII in intron 8 have been associated with lower triglyceride levels and lower cardiovascular risk in adult men. We examined the association of these lipoprotein lipase polymorphisms with high-density lipoprotein (HDL) and triglyceride levels in elderly men. Blood samples were obtained from 87 elderly men, 48 of whom had cardiovascular disease and 39 (controls) had no history of cardiovascular events. The lipoprotein lipase polymorphisms were analyzed by PCR-RFLP.

Cost-effective analysis of genotyping using oral cells in the geriatric population

T. Juárez-Cedillo, Sánchez-García, S., Mould-Quevedo, J. F., García-Peña, C., Gallo, J. J., Wagner, F. A., and Vargas-Alarcón, G., Cost-effective analysis of genotyping using oral cells in the geriatric population, vol. 9, pp. 1886-1895, 2010.

We evaluated the cost-effectiveness of using buccal swab brushes in comparison with blood samples for obtaining DNA for large epidemiological studies of the elderly population. The data reported here are from the third phase of the Integral Study of Depression among the Elderly in Mexico City’s Mexican Institute of Social Security, conducted in 2007. The total cost of the two procedures was determined.

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