EGFR

Correlation of EGFR gene amplification with invasion and metastasis of non-small cell lung cancer

X. F. Jia, Li, J., Zhao, H. B., Liu, J., and Liu, J. J., Correlation of EGFR gene amplification with invasion and metastasis of non-small cell lung cancer, vol. 14, pp. 11006-11012, 2015.

The aim of this study was to explore epidermal growth factor receptor (EGFR) gene amplification and its relationship with cancer invasion and metastasis in non-small cell lung cancer (NSCLC). EGFR amplification in 45 patients with NSCLC and 15 subjects with normal lung tissues was detected by fluorescence in situ hybridization. The relationship between EGFR amplification and the clinicopathologic features of NSCLC was analyzed.

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