E6/E7 mRNA

Expression of human papillomavirus E6 and E7 oncoprotein mRNA in women with low-grade squamous intraepithelial lesions or less

D. C. Casagrande, Ribalta, J. C. L., Leite, K. D. P. F., Schimidt, M., Speck, N. M. D. G., Casagrande, D. C., Ribalta, J. C. L., Leite, K. D. P. F., Schimidt, M., Speck, N. M. D. G., Casagrande, D. C., Ribalta, J. C. L., Leite, K. D. P. F., Schimidt, M., and Speck, N. M. D. G., Expression of human papillomavirus E6 and E7 oncoprotein mRNA in women with low-grade squamous intraepithelial lesions or less, vol. 15, p. -, 2016.

We verified the prevalence of human papillomavirus (HPV) E6/E7 protein mRNA expression in patients with low-grade squamous intraepithelial lesions (LSILs) and negative cervicovaginal cytology. To investigate the relationship between mRNA expression and viral infection type, we assessed genotyping in single infections. Samples from 825 women were submitted to the E6/E7 survey. We noticed a larger percentage of E6/E7 mRNA expression in the atypical squamous cells of undetermined significance (ASC-US) and LSIL cytologies.

HPV infection-associated anogenital cyto-colpo-histological findings and molecular typing in HIV-positive women

F. K. Tso, Rodrigues, C. L. L., Levi, J. E., Ferraz, M. G. Mattosinho, Speck, N. M. G., and Ribalta, J. C. L., HPV infection-associated anogenital cyto-colpo-histological findings and molecular typing in HIV-positive women, vol. 14, pp. 17630-17640, 2015.

HIV and human papillomavirus (HPV) coinfection is increasing, especially in the anal canal (AC) and cervico-vaginal regions. We identified anal epithelium abnormalities related to high-risk HPV (HR-HPV) lesions in the lower genital tracts (LGTs) of HIV-positive women, described the HPV genotypes identified, and assessed the expression of E6/E7 oncogenes in coinfected patients. Ninety-eight women were enrolled in groups combining HIV status and presence or absence of HPV in the LGT.

Subscribe to E6/E7 mRNA