DNA polymorphism

Genetic effect of the prolactin receptor gene on egg production traits in chickens

L. Zhang, Li, D. Y., Liu, Y. P., Wang, Y., Zhao, X. L., and Zhu, Q., Genetic effect of the prolactin receptor gene on egg production traits in chickens, vol. 11, pp. 4307-4315, 2012.

The identification and utilization of potential candidate genes with significant effects on economically important traits have become increasingly important in poultry breeding programs. The prolactin (PRLR) receptor is a specific receptor for prolactin, which is an anterior pituitary peptide hormone involved in various physiological activities and is essential for reproductive success. In chickens, the PRLR gene resides on the Z chromosome. We used a pooled DNA sequencing approach for identifying SNPs of the PRLR gene.

ABO genotyping in leukemia patients reveals new ABO variant alleles

M. C. Z. Novaretti, Domingues, A. E., Manhani, R., Pinto, E. M., Dorlhiac-Llacer, P. E., and Chamone, D. A. F., ABO genotyping in leukemia patients reveals new ABO variant alleles, vol. 7, pp. 87-94, 2008.

The ABO blood group is the most important blood group system in transfusion medicine and organ transplantation. To date, more than 160 ABO alleles have been identified by molecular investigation. Almost all ABO genotyping studies have been performed in blood donors and families and for investigation of ABO subgroups detected serologically. The aim of the present study was to perform ABO genotyping in patients with leukemia.

The mutation G298A®Ala100Thr on th coding sequence of the Duffy antigen/chemokine receptor gene in non-caucasian Brazilians

A. Cristina Estalote, Proto-Siqueira, R., Da Silva, Jr., W. Araújo, Zago, M. Antonio, and Palatnik, M., The mutation G298A®Ala100Thr on th coding sequence of the Duffy antigen/chemokine receptor gene in non-caucasian Brazilians, vol. 4, pp. 166-173, 2005.

Ala100Thr has been suggested to be a Caucasian genetic marker on the FY*B allele. As the Brazilian population has arisen from miscegenation among Portuguese, Africans, and Indians, this mutation could possibly be found in Euro- and Afro-Brazilians, or in Brazilian Indians. Fifty-three related individuals and a random sample of 100 subjects from the Brazilian population were investigated using the polymerase chain reaction and four restriction fragment length polymorphisms.

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