Downregulation of serum DKK-1 predicts poor prognosis in patients with papillary thyroid cancer
“Downregulation of serum DKK-1 predicts poor prognosis in patients with papillary thyroid cancer”, vol. 14, pp. 18886-18894, 2015.
, The Wnt inhibitor dickkopf-1 (DKK-1) has been shown to be closely correlated with tumor initiation and progression in various types of cancers. However, the serum level of DKK-1 in patients with papillary thyroid cancer (PTC) and its potential clinical significance is poorly understood. Enzyme-linked immunosorbent assay (ELISA) was used to evaluate the level of serum DKK-1 in patients with PTC (N = 132) and healthy controls (N = 40).