hBMP-7 induces the differentiation of adipose-derived mesenchymal stem cells into osteoblast-like cells
“hBMP-7 induces the differentiation of adipose-derived mesenchymal stem cells into osteoblast-like cells”, vol. 15, p. -, 2016.
, The aim of this study was to investigate the differentiation potential of adipose-derived mesenchymal stem cells (ADMSCs) into osteoblasts by human bone morphogenetic protein-7 (hBMP-7) induction. ADMSCs were isolated from the subcutaneous adipose tissue of a rabbit, and then transfected with the pcDNA3.1 vector alone and pcDNA3.1-hBMP-7 (hBMP-7), respectively. Untransfected ADMSCs were used as the control group. After transfection, the morphology and green fluorescent protein (GFP) fluorescence intensity of ADMSCs were observed by fluorescent microscopy.