Diagnosis

MicroRNAs as novel biomarkers for the differentiation of malignant versus benign thyroid lesions: a meta-analysis

G. J. Zhou, Xiao, M., Zhao, L. N., Tang, J. G., and Zhang, L., MicroRNAs as novel biomarkers for the differentiation of malignant versus benign thyroid lesions: a meta-analysis, vol. 14, pp. 7279-7289, 2015.

The aim of this meta-analysis was to systematically evaluate the diagnostic accuracy of microRNAs (miRNAs) in distinguishing malignant thyroid lesions from benign ones and to determine the potential of miRNAs as diagnostic biomarkers for thyroid cancer. The random-effect model was used to summarize the pooled estimates of diagnostic accuracy, including sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR).

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