Diabetic nephropathy

ACE insertion/deletion polymorphism and diabetic nephropathy: an evidence-based meta-analysis

L. C. Silveira, da Silva, E. G., Azevedo, R. M., Anjos, L. R. Bdos, Chagas, R. F., Alcântara, E. C., Santos, R. S., and Reis, A. A. S., “ACE insertion/deletion polymorphism and diabetic nephropathy: an evidence-based meta-analysis”, Genetics and Molecular Research, vol. 18, no. 3, 2019.

Evaluation of associations between single nucleotide polymorphisms in the FRMD3 and CARS genes and diabetic nephropathy in a Kuwaiti population

S. Al-waheeb, Alwohhaib, M., Abdelghani, A., Al-Sharrah, S., Al-Shafey, E., Al-Sahow, A., Alyatama, N., Dashti, A. A., Hussain, N., Al-waheeb, S., Alwohhaib, M., Abdelghani, A., Al-Sharrah, S., Al-Shafey, E., Al-Sahow, A., Alyatama, N., Dashti, A. A., Hussain, N., Al-waheeb, S., Alwohhaib, M., Abdelghani, A., Al-Sharrah, S., Al-Shafey, E., Al-Sahow, A., Alyatama, N., Dashti, A. A., and Hussain, N., “Evaluation of associations between single nucleotide polymorphisms in the FRMD3 and CARS genes and diabetic nephropathy in a Kuwaiti population”, vol. 15, p. -, 2016.

Diabetic nephropathy is the leading cause of end-stage kidney disease in the world. Many single nucleotide polymorphisms (SNPs) have been associated with diabetic nephropathy. SNPs at the 4.1 protein ezrin, radixin, moesin domain 3 (FRMD3) and cysteinyl t-RNA synthetase (CARS) genes have a well-established relationship with diabetic nephropathy. However, this association has not been evaluated in a Kuwaiti population.

Correlation between polymorphisms of hypoxia-inducible factor-1α Pro582Ser and type 2 diabetic nephropathy

Y. X. Bi, Yu, L., and Jin, G. X., “Correlation between polymorphisms of hypoxia-inducible factor-1α Pro582Ser and type 2 diabetic nephropathy”, vol. 14, pp. 14503-14509, 2015.

We examined the correlation between gene polymorphisms in hypoxia-inducible factor-1α (HIF-1α) Pro582Ser and type 2 diabetic nephropathy (DN). A total of 244 subjects with type 2 diabetes were recruited. The 1285-bp locus polymorphism of HIF-1α exon was detected using polymerase chain reaction-restriction fragment length polymorphism. C/T single nucleotide polymorphisms were detected at the site of 1285 bp of the HIF-1α exon, from a proline to a serine (Pro582Ser). The frequency of CT heterozygotes was significantly higher in DN patients than in diabetes patients (P

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