Dendritic cell

Immune function of nonparenchymal liver cells

X. K. Xing, Wu, H. Y., Feng, H. G., Yuan, Z. Q., Xing, X. K., Wu, H. Y., Feng, H. G., Yuan, Z. Q., Xing, X. K., Wu, H. Y., Feng, H. G., and Yuan, Z. Q., Immune function of nonparenchymal liver cells, vol. 15, p. -, 2016.

The liver is the human body largest digestive and metabolic organ, and a very important immune organ. This paper discusses the location and morphology of hepatic sinusoidal endothelial cells, dendritic cells, hepatic stellate cells, and Kupffer cells in the liver and their role in regulating immune functions. Therefore, here we provide a preliminary understanding of the immune regulatory function of liver cells, and information on the occurrence and treatment of liver diseases.

Stimulation of dendritic cell maturation and induction of apoptosis in lymphoma cells by a stable lectin from buckwheat seeds

C. Z. Bai, Ji, H. J., Feng, M. L., Hao, X. L., Zhong, Q. M., Cui, X. D., and Wang, Z. H., Stimulation of dendritic cell maturation and induction of apoptosis in lymphoma cells by a stable lectin from buckwheat seeds, vol. 14, pp. 2162-2175, 2015.

The present study aims to purify and characterize lectin from tartary buckwheat seeds and study its properties as well as biological activities to determine its possible biomedical applications in promoting maturation and proliferation of peripheral blood DCs derived from healthy donors and to study the effect of inducing apoptosis in human leukemia U937 cells. A novel tartary buckwheat lectin (TBL) protein, purified from tartary buckwheat seeds, showed a single band with a molecular mass of 65 kDa in SDS-PAGE.

Anti-prostate cancer effects of CTL cell induction in vitro by recombinant adenovirus mediated PSMA/4-1BBL dendritic cells: an immunotherapy study

C. - G. Sui, Wu, D., Meng, F. - D., Yang, M. - H., and Jiang, Y. - H., Anti-prostate cancer effects of CTL cell induction in vitro by recombinant adenovirus mediated PSMA/4-1BBL dendritic cells: an immunotherapy study, vol. 14, pp. 7208-7217, 2015.

This study aimed to examine anti-prostate cancer immune response induced by dendritic cells (DCs) transduced with PSMA/4-1BBL recombinant adenoviruses in vitro. Ad-PSMA, Ad-4-1BBL, and Ad-GFP were transfected into DCs derived from peripheral blood of healthy volunteers. Ad-PSMA/4-1BBL-DC, Ad-PSMA-DC, Ad-4-1BBL-DC, Ad-GFP-DC, and normal-DC, PSMA and 4-1BBL protein levels in DCs were detected by western blot. IL-12, IFN-γ and IL-10 were measured by ELISA.

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