Decoherence

Decoherence in yeast cell populations and its implications for genome-wide expression noise

M. R. S. Briones and Bosco, F., Decoherence in yeast cell populations and its implications for genome-wide expression noise, vol. 8, pp. 47-51, 2009.

Gene expression “noise” is commonly defined as the stochastic variation of gene expression levels in different cells of the same population under identical growth conditions. Here, we tested whether this “noise” is amplified with time, as a consequence of decoherence in global gene expression profiles (genome-wide microarrays) of synchronized cells. The stochastic component of transcription causes fluctuations that tend to be amplified as time progresses, leading to a decay of correlations of expression profiles, in perfect analogy with elementary relaxation processes.

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