Cytochrome P450 17

Polymorphisms in CYP17, COMT, and ESR1 genes in women after menopause and association with bone mineral density

C. G. Gonçalves, Almeida, B. C., Camargo-Kosugi, C. M., Costa, A. M. M., Silva, I. D. C. G., and Haidar, M. A., Polymorphisms in CYP17, COMT, and ESR1 genes in women after menopause and association with bone mineral density, vol. 14, pp. 15802-15810, 2015.

In this study, we evaluated genetic factors related to the mineral density during post-menopause. We evaluated 110 women in the first 5 years post-menopause, without previous hormone replacement therapy. Cytochrome P450 17 (CYP17) (rs743572), catechol-O-methyl transferase (COMT) (rs4680), and estrogen receptor 1 (ESR1) (rs9322331) were examined for the presence of polymorphisms.

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