Cytochrome P450

Meta-analysis of correlation between the CYP1A2 -3860 G > A polymorphism and lung cancer risk

J. Ren, He, B. Z., Zhang, T. S., Lu, S. P., Yan, T., Ren, J., He, B. Z., Zhang, T. S., Lu, S. P., and Yan, T., Meta-analysis of correlation between the CYP1A2 -3860 G > A polymorphism and lung cancer risk, vol. 15, p. -, 2016.

The aim of this meta-analysis was to assess the association between a polymorphism (-3860 G > A) in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer susceptibility. Relevant studies were retrieved from the PubMed and EMBase databases, and additionally evaluated for conformance with the inclusion criteria. The odds ratios (ORs) and their 95% confidence intervals (95%CIs) in all selected studies were used to assess the relationship between the CYP1A2 -3860 G > A polymorphism and lung cancer risk. The data was pooled using Stata v.11.

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