CYP1 A1

Interaction of the CYP1A1 gene polymorphism and smoking in non-small cell lung cancer susceptibility

Y. Q. Xie, Chen, J. M., and Liu, Y., Interaction of the CYP1A1 gene polymorphism and smoking in non-small cell lung cancer susceptibility, vol. 14, pp. 19411-19417, 2016.

Many studies have shown that genetic factors, environmental factors, and bad living habits, especially smoking, are risk factors for lung cancer. However, not all smokers develop lung cancer, which may be related to different genetic backgrounds. Currently, most research has investigated the GSTM1, XRCC1, XRCC3, CYP2D6, and C188T genes. Little research has been done on the cytochrome P450 (CYP) 1A1 gene, and results have varied.

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