CXCL12 G801A polymorphism

CXCL12 G801A polymorphism and susceptibility to glioma: a case‑control study

S. F. Chang, Li, S. L., Yang, B., Yao, K. M., Miao, R. H., Liang, G. F., and Zhang, K. M., CXCL12 G801A polymorphism and susceptibility to glioma: a case‑control study, vol. 14, pp. 17399-17405, 2015.

Previous studies have demonstrated that the CXCL12 G801A polymorphism is closely correlated with tumor susceptibility. In addition, the CXCL12/CXCR4 pathway is closely related to proliferation, metastasis, and invasion of glioma. However, the genetic effects of the CXCL12 G801A polymorphism on glioma risk in Chinese populations remain unknown. In this study, we investigated the potential associations between the CXCL12 G801A polymorphism with glioma susceptibility and its clinicopathological characteristics.

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