Coronary artery disease

Role of interleukin-10 gene polymorphisms in the development of coronary artery disease in Chinese population

H. M. Xu and Liu, Y. R., Role of interleukin-10 gene polymorphisms in the development of coronary artery disease in Chinese population, vol. 14, pp. 15869-15875, 2015.

The aim of this study was to investigate the association between three common SNPs (-1082A/G, -819T/C, and -592A/C) in the interleukin 10 (IL-10) gene, and the development of coronary artery disease. Between January 2013 and December 2014, 272 patients with coronary artery disease and control subjects (each) were recruited for this study from the Huaihe Hospital of Henan University. The IL-10-1082A/G, -819T/C and -592A/C gene polymorphisms were analyzed using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay.

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