Control mechanism

Expression profiles of variation integration genes in bladder urothelial carcinoma

J. M. Wang, Wang, Y. Q., Gao, Z. L., Wu, J. T., Shi, B. K., and Yu, C. C., Expression profiles of variation integration genes in bladder urothelial carcinoma, vol. 13, pp. 3486-3494, 2014.

Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to construct a causal-target module network of the range of bladder cancer-related genomes. Here, we explored the control mechanism underlying bladder cancer phenotype expression regulation by the major bladder cancer genes.

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