Complement component C7

A 425 T>C polymorphism in complement C7 association with resistance to Aeromonas hydrophila in grass carp

Y. B. Shen, Zhang, J. B., Fu, J. J., Xu, X. Y., Li, J. L., Wang, R. Q., Xuan, Y. F., Shen, Y. B., Zhang, J. B., Fu, J. J., Xu, X. Y., Li, J. L., Wang, R. Q., Xuan, Y. F., Shen, Y. B., Zhang, J. B., Fu, J. J., Xu, X. Y., Li, J. L., Wang, R. Q., and Xuan, Y. F., A 425 T>C polymorphism in complement C7 association with resistance to Aeromonas hydrophila in grass carp, vol. 15, p. -, 2016.

Aeromonas hydrophila, a widespread bacterium in the aquatic environment, causes hemorrhagic septicemia in fish. In the last decade, the disease has caused mass mortalities and tremendous economic loss in cultured fish. The complement component C7 is a terminal component of complement that interacts in a sequence of polymerization reactions with other terminal complement components to form a membrane attack complex. The formation of the membrane attack complex creates a pore in the membranes of certain pathogen that can lead to their death.

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