Colorectal carcinoma

GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population

M. N. Khabaz, Nedjadi, T., Gari, M. A., Al-Maghrabi, J. A., Atta, H. M., Bakarman, M., Gazzaz, Z. J., Khabaz, M. N., Nedjadi, T., Gari, M. A., Al-Maghrabi, J. A., Atta, H. M., Bakarman, M., Gazzaz, Z. J., Khabaz, M. N., Nedjadi, T., Gari, M. A., Al-Maghrabi, J. A., Atta, H. M., Bakarman, M., and Gazzaz, Z. J., GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population, vol. 15, p. -, 2016.

The enzyme glutathione S-transferase Mu 1 (GSTM1) is encoded by the GSTM1 gene. Polymorphisms in GSTM1 affect the detoxifying function of the enzyme variants. This forms the basis of the debate about the impact of the GSTM1 null/present genotype on colorectal carcinoma risk. We tested the potential influence of GSTM1 polymorphisms on the development of colorectal cancer.

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