Colorectal cancer cell HCT116

5-Fluorouracil induces apoptosis of colorectal cancer cells

J. T. Zhang, Zhou, W. L., He, C., Liu, T., Li, C. Y., Wang, L., Zhang, J. T., Zhou, W. L., He, C., Liu, T., Li, C. Y., and Wang, L., 5-Fluorouracil induces apoptosis of colorectal cancer cells, vol. 15, p. -, 2016.

5-Fluorouracil (5-FU) is widely used in chemotherapy for treatment of colorectal cancer. Leucine-rich repeat-containing G protein-coupled receptor (LGR) is known to participate in the occurrence and development of breast cancer by regulating the rebirth of tumor vessels. This study aimed to explore the proliferation and apoptosis of HCT116 colorectal cancer cells treated with 5-FU and related molecular mechanisms. 5-FU (20 μg/mL) was used to treat cultured HCT116 cells.

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