Colloid chemistry

Role of aluminum adjuvant in producing an allergic rhinitis animal model

L. Xi, Fan, E., Zhao, Y., Li, Y., Zhang, Y., and Zhang, L., Role of aluminum adjuvant in producing an allergic rhinitis animal model, vol. 13, pp. 5173-5181, 2014.

This study evaluated different dosage forms of aluminum adjuvant in generating allergic rhinitis animal models. Forty female BALB/c mice were assigned to four groups, including three dosage forms of aluminum adjuvant [powder, gel, and hydrosolvent of aluminum hydroxide, Al(OH)3] mixed with ovalbumin to simulate the symptoms of allergic rhinitis and one control group. Although the aluminum adjuvants were in different dosage forms, the content was 5 mg after conversion in all groups. The fourth group was given normal saline instead as a control.

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