Collagen type I

Atomized paclitaxel liposome inhalation treatment of bleomycin-induced pulmonary fibrosis in rats

Y. Zhou, Zhu, W. P., Cai, X. J., Chen, M., Zhou, Y., Zhu, W. P., Cai, X. J., Chen, M., Zhou, Y., Zhu, W. P., Cai, X. J., and Chen, M., Atomized paclitaxel liposome inhalation treatment of bleomycin-induced pulmonary fibrosis in rats, vol. 15, p. -, 2016.

We sought to determine the efficacy of atomized paclitaxel liposome inhalation treatment of pulmonary fibrosis in a bleomycin-induced rat model. Forty male Sprague-Dawley rats were randomly divided into four groups: healthy control, pulmonary fibrosis without treatment, paclitaxel liposome inhalation-treated, and intravenous paclitaxel liposome-treated. Fibrosis was induced by bleomycin injection. A total of 20 mg/kg paclitaxel liposome was administered by inhalation every other day for a total of 10 doses.

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