Clinical samples

Specific BRCA1 gene variations amongst young Moroccan breast cancer patients

A. Tazzite, Nadiffi, S., Kottwitz, D., M. Amrani, E., Jouhadi, H., Benider, A., Moumen, A., and Sefrioui, H., Specific BRCA1 gene variations amongst young Moroccan breast cancer patients, vol. 13, pp. 791-798, 2014.

Germline mutations in the BRCA1 gene are known predictive markers for the development of hereditary breast cancer. Nevertheless, no comprehensive study has been performed targeting the presence and relevance of BRCA1 mutations in Moroccan breast cancer patients. We here present an analysis of BRCA1 gene regions (exon 2 and exon 11a/b) of 50 female Moroccan breast cancer patients with early disease onset (≤40 years) or familial disease backgrounds.

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