Chemotherapy resistance

Gene expression profiling of epithelial ovarian cancer reveals key genes and pathways associated with chemotherapy resistance

M. Zhang, Luo, S. C., Zhang, M., Luo, S. C., Zhang, M., and Luo, S. C., Gene expression profiling of epithelial ovarian cancer reveals key genes and pathways associated with chemotherapy resistance, vol. 15, p. -, 2016.

The aim of this study is to analyze gene expression data to identify key genes and pathways associated with resistance to platinum-based chemotherapy in epithelial ovarian cancer (EOC) and to improve clinical treatment strategies. The gene expression data set was downloaded from Gene Expression Omnibus and included 12 chemotherapy-resistant EOC samples and 16 chemotherapy-sensitive EOC samples. A differential analysis was performed to screen out differentially expressed genes (DEGs).

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