Glutathione S-transferase polymorphisms influence chemotherapy response and treatment outcome in breast cancer
“Glutathione S-transferase polymorphisms influence chemotherapy response and treatment outcome in breast cancer”, vol. 14, pp. 11126-11132, 2015.
, The aim of this study was to evaluate the role of GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms in the clinical response to chemotherapy and treatment outcome of patients with breast cancer. A total of 262 subjects were randomly selected from among patients with a histologically confirmed breast cancer. The genotypes of GSTM1, GSTT1, and GSTP1 IIe105Val polymorphisms were determined by polymerase chain reaction-restriction fragment length polymorphism analysis.