Effects of genetic variants of CCR5 chemokine receptors on oral squamous cell carcinoma
“Effects of genetic variants of CCR5 chemokine receptors on oral squamous cell carcinoma”, vol. 12, pp. 5714-5720, 2013.
, We aimed to evaluate the effect of genetic variants of the chemokine C-C motif receptor (CCR5) in the pathogenesis of oral squamous cell carcinoma (OSCC). A total of 127 patients diagnosed with OSCC and 104 healthy individuals were included in the study. The polymorphisms CCR5 59029 and CCR5-delta32 were assessed with the polymerase chain reaction-restricted fragment length polymorphism (PCR-RFLP) method from peripheral blood samples of both groups. There was a statistically significant difference between the control and patient groups for CCR5 59029 A/G genotypes (P 0.05).