CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
“CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis”, vol. 14, pp. 5203-5209, 2015.,
Cytochrome P4502E1 (CYP2E1) is a key enzyme in the metabolic activation of many carcinogens, but the roles of CYP2E1 polymorphisms in cervical neoplasia (CN) are inconclusive. Published case-control cohort studies from the Pubmed, Embase, and China National Knowledge Infrastructure databases were retrieved. Data were extracted and pooled odds ratios with 95% confidence intervals were calculated. Seven studies examining 1097 cases and 1117 controls were included in this meta-analysis.