Cervical intraepithelial neoplasia

Prevalence of human papillomavirus genotypes among women with cervical lesions in the Shaanxi Province of China

J. Li, Wang, Y. Y., Nan, X., Tian, X. F., Yan, T., Wang, P., Yin, Y., Liu, Y., Yuan, R., Wang, G. Q., Fu, Y. L., Li, J., Wang, Y. Y., Nan, X., Tian, X. F., Yan, T., Wang, P., Yin, Y., Liu, Y., Yuan, R., Wang, G. Q., Fu, Y. L., Li, J., Wang, Y. Y., Nan, X., Tian, X. F., Yan, T., Wang, P., Yin, Y., Liu, Y., Yuan, R., Wang, G. Q., and Fu, Y. L., “Prevalence of human papillomavirus genotypes among women with cervical lesions in the Shaanxi Province of China”, vol. 15, p. -, 2016.

This study aimed to investigate human papilloma virus (HPV) genotypes among women with cervical lesions in Shaanxi Province, China, to obtain information regarding cervical lesion prevention and treatment. The study included 4508 HPV-positive subjects; cervical swab specimens were collected and tested for HPV infection status and HPV genotypes using polymerase chain reaction and reverse dot-blot hybridization.

Clinical significance of serum miR-196a in cervical intraepithelial neoplasia and cervical cancer

P. Liu, Xin, F., and Ma, C. F., “Clinical significance of serum miR-196a in cervical intraepithelial neoplasia and cervical cancer”, vol. 14, pp. 17995-18002, 2015.

Previous studies have reported that miR-196a is upregulated in cervical cancer tissues and cell lines. However, whether serum miR-196a is increased in patients with cervical cancer or cervical intraepithelial neoplasia (CIN), and its potential clinical value remained unknown. In total, 105 cervical cancer patients, 86 CIN patients, and 50 healthy volunteers were recruited. Quantitative reverse transcription-polymerase chain reaction was performed to compare the serum levels miR-196a in all participants.

Molecular analysis and conventional cytology: association between HPV and bacterial vaginosis in the cervical abnormalities of a Brazilian population

A. L. Peres, Camarotti, J. R. S. L., Cartaxo, M., Alencar, N., Stocco, R. C., Beçak, W., Pontes-Filho, N. T., Araújo, R. F. F., Lima-Filho, J. L., and Martins, D. B. G., “Molecular analysis and conventional cytology: association between HPV and bacterial vaginosis in the cervical abnormalities of a Brazilian population”, vol. 14, pp. 9497-9505, 2015.

We investigated the association between bacterial vaginosis (BV) and human papillomavirus (HPV) infection in Papanicolaou smears in a Brazilian population. Cross-sectional analysis was performed on 673 samples collected from women attending public health centers in Olinda (PE, Brazil) by conventional cytology methodology and molecular analysis, PCR tests (GP5+/6+ and MY09/11). Cytological abnormalities, BV, and HPV-DNA were detected in 23 (3.4%) samples, 189 samples (28.1%), and 210 samples (31.2%), respectively.

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