Absence of toxicity and genotoxicity in an extract of Rubus coriifolius.
, “Absence of toxicity and genotoxicity in an extract of Rubus coriifolius.”, Genet Mol Res, vol. 15, no. 4, 2016.
Cell proliferation
Hypoxia facilitates epithelial-mesenchymal transition-mediated rectal cancer progress.
, “Hypoxia facilitates epithelial-mesenchymal transition-mediated rectal cancer progress.”, Genet Mol Res, vol. 15, no. 4, 2016.
microRNA 421 induces apoptosis of c-33a cervical cancer cells via down-regulation of Bcl-xL.
, “microRNA 421 induces apoptosis of c-33a cervical cancer cells via down-regulation of Bcl-xL.”, Genet Mol Res, vol. 15, no. 4, 2016.
Hypoxia enhances periodontal ligament stem cell proliferation via the MAPK signaling pathway
, “Hypoxia enhances periodontal ligament stem cell proliferation via the MAPK signaling pathway”, vol. 15, no. 4, p. -, 2016.
INTRODUCTION
Histone H3K9 acetylation influences growth characteristics of goat adipose-derived stem cells in vitro
, “Histone H3K9 acetylation influences growth characteristics of goat adipose-derived stem cells in vitro”, vol. 15, no. 4, p. -, 2016.
INTRODUCTION
Kallikrein 12 downregulation reduces AGS gastric cancer cell proliferation and migration
, “Kallikrein 12 downregulation reduces AGS gastric cancer cell proliferation and migration”, vol. 15, p. -, 2016.
Abnormal expression of the kallikrein (KLK) family of serine proteases closely correlates with onset, progression, and prognosis of endocrine gland-related malignant tumors. The aim of this study was to evaluate how downregulation of KLK12 influenced cell cycle and proliferation of the AGS gastric cancer cell line. KLK12 was detected by western blot in GES-1 normal gastric epithelial and AGS cells.
Propofol induces apoptosis and inhibits the proliferation of rat embryonic neural stem cells via gamma-aminobutyric acid type A receptor
, “Propofol induces apoptosis and inhibits the proliferation of rat embryonic neural stem cells via gamma-aminobutyric acid type A receptor”, vol. 14, pp. 14920-14928, 2015.
We investigated the effect of propofol on the proliferation and viability of rat embryonic neural stem cells (rENSCs) and the potential mechanisms involved. rENSCs were isolated and cultured in vitro and treated with 1, 10, or 50 μM propofol, while the control group was treated with 0.1 μM dimethyl sulfoxide. The effect of propofol on the proliferation and viability of rENSCs was examined by proliferation and apoptosis assays. Real-time polymerase chain reaction was employed to analyze the mRNA expression of checkpoint kinase 1 (Chk1) and p53 in rENSCs exposed to propofol.
Aquaporin in the proliferation and apoptosis of diabetic myocardial cells
, “Aquaporin in the proliferation and apoptosis of diabetic myocardial cells”, vol. 14, pp. 17366-17372, 2015.
The aim of this study was to explore the effect of aquaporin on the molecular mechanism of human diabetic myocardial cell apoptosis. The methylthiazolyle tetrazolium assay was used to detect the inhibitory effect of different concentrations of aquaporin on cell growth. The rate of aquaporin-induced myocardial cell apoptosis was detected by flow cytometric analysis of Annexin V-fluorescein isothiocyanate/propidium iodide double-stained cells. We also attempted to quantify the expression of Bcl-2, Bax, caspase-3, and survivin in diabetic myocardial cells by western blot analysis.
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