Construction of a gene-gene interaction network with a combined score across multiple approaches
“Construction of a gene-gene interaction network with a combined score across multiple approaches”, vol. 14, pp. 7018-7030, 2015.
, Recent progress in computational methods for investigating physical and functional gene interactions has provided new insights into the complexity of biological processes. An essential part of these methods is presented visually in the form of gene interaction networks that can be valuable in exploring the mechanisms of disease. Here, a combined network based on gene pairs with an extra layer of reliability was constructed after converting and combining the gene pair scores using a novel algorithm across multiple approaches.