Case-control study

Association between TNF-αrs1799724 and rs1800629 polymorphisms and the risk of Crohn’s disease

Y. Q. Mao, Dong, S. Q., and Gao, M., Association between TNF-αrs1799724 and rs1800629 polymorphisms and the risk of Crohn’s disease, vol. 14, pp. 15811-15821, 2015.

We investigated the associations between 2 major tumor necrosis factor-α (TNF-α) polymorphisms, rs1799724 C>T and rs1800629 G>A, and the susceptibility to Crohn’s disease (CD) using a meta-analysis framework. The PubMed, EBSCO, Ovid, Wiley, Web of Science, WANFANG, and VIP databases (last updated search in October 2014) were comprehensively searched for relevant published studies.

Correlations between the COMT gene rs4680 polymorphism and susceptibility to ovarian cancer

W. Pan and Liao, H., Correlations between the COMT gene rs4680 polymorphism and susceptibility to ovarian cancer, vol. 14, pp. 16813-16818, 2015.

The objective of this study was to perform a systematic review of the correlations between the single nucleotide polymorphism rs4680 in the catechol-O-methyltransferase (COMT) gene and susceptibility to ovarian cancer. A computer search was carried out for relevant case-control studies published between January 2000 to January 2014 in databases such as Ovid, EBSCO, PubMed, CNKI, CBMDISC, VIP, and WanFang Data. The literature was screened based on inclusion and exclusion criteria.

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