Significance of sarcomere gene mutation in patients with dilated cardiomyopathy
“Significance of sarcomere gene mutation in patients with dilated cardiomyopathy”, vol. 14, pp. 11200-11210, 2015.,
Dilated cardiomyopathy (DCM) is a myocardial disease with a high mortality rate. Approximately 40 genes have been found to be associated with DCM to date. Non-familial DCM can also be caused by gene mutations, suggesting that genetic factors were involved in the pathogenesis of DCM; therefore genetic testing is beneficial for the early diagnosis of DCM, which can facilitate the implementation of preventive measures by and within patient’s families. Here, we investigated the underlying genetic mutations involved in the cause of patients with DCM.