Caffeic acid

In vitro genotoxicity assessment of caffeic, cinnamic and ferulic acids

E. L. Maistro, Angeli, J. P. F., Andrade, S. F., and Mantovani, M. S., In vitro genotoxicity assessment of caffeic, cinnamic and ferulic acids, vol. 10, pp. 1130-1140, 2011.

Phenols are a large and diverse class of compounds, many of which occur naturally in a variety of food plants; they exhibit a wide range of biological effects, including antibacterial, anti-inflammatory, antiallergic, hepatoprotective, antithrombotic, antiviral, anticarcinogenic, and vasodilatory actions. We examined the genotoxic and clastogenic potential of three phenolic compounds: caffeic, cinnamic and ferulic acids, using the comet and micronucleus assays in vitro. Drug-metabolizing rat hepatoma tissue cells (HTCs) were used.

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