In vitro genotoxicity assessment of caffeic, cinnamic and ferulic acids
“In vitro genotoxicity assessment of caffeic, cinnamic and ferulic acids”, vol. 10, pp. 1130-1140, 2011.
, Phenols are a large and diverse class of compounds, many of which occur naturally in a variety of food plants; they exhibit a wide range of biological effects, including antibacterial, anti-inflammatory, antiallergic, hepatoprotective, antithrombotic, antiviral, anticarcinogenic, and vasodilatory actions. We examined the genotoxic and clastogenic potential of three phenolic compounds: caffeic, cinnamic and ferulic acids, using the comet and micronucleus assays in vitro. Drug-metabolizing rat hepatoma tissue cells (HTCs) were used.