C2C12 cells

Promoter analysis of bovine cardiomyopathy-associated protein 1 gene

G. N. Sui, Liu, Z. W., Wang, T., Li, X., Ding, X. B., Liu, X. F., Guo, H., Sui, G. N., Liu, Z. W., Wang, T., Li, X., Ding, X. B., Liu, X. F., and Guo, H., Promoter analysis of bovine cardiomyopathy-associated protein 1 gene, vol. 15, p. -, 2016.

The CMYA1 (cardiomyopathy-associated protein 1) is an actin-binding protein that plays a vital role in cardiac morphogenesis. CMYA1 is expressed specifically in the myocardial and skeletal muscle and is up-regulated in injured muscle. We therefore speculated that the bovine CMYA1 promoter might be muscle-specific. In this study, the promoter (+20/-1135) region of the bovine CMYA1 gene was cloned into a pEGFP-1 vector, and we found that the EGFP was observed only in C2C12 and myoblast cells. Thus, the CMYA1 promoter is muscle-specific.

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