Breast cancer

Protein-protein interaction between ezrin and p65 in human breast cancer cells

R. Tang, Li, F. X., Shao, W. F., Wen, Q. S., Yu, X. R., Xiong, J. B., Tang, R., Li, F. X., Shao, W. F., Wen, Q. S., Yu, X. R., and Xiong, J. B., Protein-protein interaction between ezrin and p65 in human breast cancer cells, vol. 15, p. -, 2016.

Our study aimed to investigate the co-localization and protein-protein interactions between ezrin and p65 in human breast cancer cells. Liquid chromatography-mass spectrometry (LCMS) was used to uncover novel protein interactions with ezrin in MDA-MB-231 cells. Endogenous co-immunoprecipitation was used to validate protein-protein interactions between ezrin and p65 in MDA-MB-231. Exogenous interactions between ezrin and p65 were validated in MDA-MB-231 cells via Flag-ezrin and HA-p65 co-transfection and followed by co-immunoprecipitation.

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