Breast cancer

Validation of associations between ESR1 variants and breast cancer risk in Chinese cohorts

X. Li, Yao, G. Y., Li, F. X., Qiu, Y. R., Yang, X. X., Li, X., Yao, G. Y., Li, F. X., Qiu, Y. R., and Yang, X. X., Validation of associations between ESR1 variants and breast cancer risk in Chinese cohorts, vol. 15, p. -, 2016.

Estrogen receptor-a (ER) protein plays a key role in breast carcinogenesis, and common genetic variants in the corresponding gene locus have been associated with breast cancer risk in different populations. Here, we analyzed estrogen receptor 1 (ESR1) associations in two hospital-based studies of patients from the south of China.

Increased risk of breast cancer in individuals carrying the TNRC9 rs3803662 C>T polymorphism: a meta-analysis of case-control studies

Q. Wang, Wang, N. Y., Cao, X. M., Sun, X., Shen, D., Yuan, M., Chen, J. F., Wang, Q., Wang, N. Y., Cao, X. M., Sun, X., Shen, D., Yuan, M., and Chen, J. F., Increased risk of breast cancer in individuals carrying the TNRC9 rs3803662 C>T polymorphism: a meta-analysis of case-control studies, vol. 15, p. -, 2016.

Currently, the relationship between the trinucleotide repeat containing 9 (TNRC9) rs3803662 C>T polymorphism and risk of breast cancer (BC) is uncertain. Here, we attempted to obtain a more accurate assessment of this association by conducting a meta-analysis of all eligible case-control investigations, comprising 44,820 cases and 58,316 controls. A comprehensive search was performed to identify all suitable studies involving the TNRC9 rs3803662 polymorphism and BC risk.

Subscribe to Breast cancer