Breast cancer

Predictive potential role of glutathione S-transferases polymorphisms in response to chemotherapy and breast cancer prognosis

P. Yuan, Yuan, L., Xu, B. L., Wang, C. Z., Yang, H. Z., and Li, Y., Predictive potential role of glutathione S-transferases polymorphisms in response to chemotherapy and breast cancer prognosis, vol. 14, pp. 16675-16681, 2015.

The aim of this study was to evaluate the role of GSTM1 null/present, GSTT1 null/present, and GSTP1 polymorphisms in the clinical response to chemotherapy and treatment outcome of breast cancer. The GSTM1, GSTT1, and GSTP1 IIe105Val polymorphism genotypes were analyzed using polymerase chain reaction coupled with restriction fragment length polymorphism.

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