Bradykinin

Effect of bradykinin on renal mesangial cell proliferation and extracellular matrix secretion

C. Y. Liu, Zhou, L. L., Cheng, Q., Jiang, S. N., Sheng, J., Sun, J. D., and Zhao, J. Y., Effect of bradykinin on renal mesangial cell proliferation and extracellular matrix secretion, vol. 13, pp. 490-498, 2014.

Recent studies have found that bradykinin (BK) plays a role in delaying glomerulosclerosis, although the mechanism of this phenomenon remains unclear. Mesangial cell proliferation (MCP) and extracellular matrix (ECM) secretion are important mechanisms for glomerulosclerosis. This study investigated the impact of BK on the platelet-derived growth factor (PDGF)-induced proliferation of mesangial cells, and evaluated its correlations with the extracellular signal-related kinase (ERK) signaling pathway.

Subscribe to Bradykinin