E. E. Engel, Nogueira-Barbosa, M. H., Brassesco, M. S., Silva, G. E. B., Valera, E. T., Peria, F. M., Motta, T. C., and Tone, L. G.,
“Osteosarcoma arising from osteochondroma of the tibia: case report and cytogenetic findings”, vol. 11. pp. 448-454, 2012.
Osteochondroma is a cartilage capped benign tumor developing mainly at the juxta-epiphyseal region of long bones. The rate of malignant transformation, mainly into chondrosarcoma, is estimated to be less than 1-3%. Transformation into osteosarcoma is very rare and has been reported only thirteen times. There is little information on treatment and outcome. We report the case of a secondary osteosarcoma arising in the left tibia of a 23-year-old male, 10 years after the initial diagnosis of osteochondroma and after two partial resections.
