Bone marrow failure

Abnormal metabolites related to bone marrow failure in aplastic anemia patients

P. Zhong, Zhang, J., and Cui, X., Abnormal metabolites related to bone marrow failure in aplastic anemia patients, vol. 14, pp. 13709-13718, 2015.

Metabolomics is the identification and quantitation of small molecules that are involved in metabolic reactions. Liquid chromatography-mass spectrometry (LC-MS) has enjoyed growing popularity as the platform for metabolomic studies due to high throughput, soft ionization, and good coverage of metabolites. Serum metabolites of aplastic anemia (AA) patients and healthy controls were investigated using LC-MS. A wavelet-based method was utilized to find and align LC-MS peaks.

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