Body measurement

Polymorphisms in the SIRT5 gene and their association with body measurement and ultrasound traits in Qinchuan cattle

L. S. Gui, Wang, H. C., Liu, G. Y., and Zan, L. S., “Polymorphisms in the SIRT5 gene and their association with body measurement and ultrasound traits in Qinchuan cattle”, vol. 14, pp. 3843-3853, 2015.

Silent information regulator 5 (SIRT5), a member of the Sirtuin family class III nicotinamide adenine dinucleotide-dependent protein deacetylases, plays an important role in metabolic and aging processes in mammals. We identified 4 single-nucleotide polymorphisms (SNPs) (G22010A, G22052A, G22119T, and G22245C) in the 3' untranslated regions of the SIRT5 gene from 572 Qinchuan cattle by sequencing and investigating their association with growth and ultrasound traits. The frequencies of genotype GG and allele G were high at the 4 SNPs.

New polymorphisms in the novel LYRM1 gene are associated with body measurement and meat quality traits in Qinchuan cattle

Y. K. Li, Huangpu, Y. F., Gao, J. B., Yang, N., Fu, C. Z., Wang, H. B., Cheng, G., and Zan, L. S., “New polymorphisms in the novel LYRM1 gene are associated with body measurement and meat quality traits in Qinchuan cattle”, vol. 13, pp. 6926-6936, 2014.

Body measurement and meat quality traits play important roles in the evaluation of productivity in cattle; they are influenced by genetic and environmental factors. Recent studies have shown that LYRM1 is a novel gene related to obesity and may influence fat deposition. We screened for new polymorphisms in the bovine LYRM1 gene and analyzed their association with body measurement and meat quality traits in cattle. DNA samples were obtained from 572 Qinchuan cattle aged from 18 to 24 months. DNA sequencing was used to find the LYRM1 single nucleotide polymorphisms (SNPs).

Association of SIRT2 gene polymorphisms with body measurement and growth traits of Qinchuan cattle

L. S. Gui, Yang, W. C., Zhao, C. P., Wei, S. J., Zhao, Z. D., and Zan, L. S., “Association of SIRT2 gene polymorphisms with body measurement and growth traits of Qinchuan cattle”, vol. 13, pp. 8834-8844, 2014.

Silent information regulator 2 (SIRT2), a member of the Sirtuin family of class III nicotinamide adenine dinucleotide-dependent protein deacetylases, plays an important role in senescence, metabolism, and apoptosis. This study was conducted to detect potential polymorphisms of the bovine SIRT2 gene and explore their relationships with meat quality and body measurement traits (BMTs) in Qinchuan cattle.

Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene

Y. F. Liu, Zan, L. S., Cui, W. T., Xin, Y. P., Jiao, Y., and Li, K., “Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene”, vol. 10, pp. 1777-1786, 2011.

Cyclin-dependent kinase 6 (CDK6) is a key element of D-type cyclin holoenzymes. It is involved in the regulation of the G1-phase of the cell cycle and is considered to be an important candidate gene for selection of body measurement traits through marker-assisted selection. We cloned the promoter sequence of this gene in bovines and found it to share high similarity with that of the human CDK6 promoter.

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