Body mass index

Exome sequencing in Thai patients with familial obesity

S. Kaewsutthi, Santiprabhob, J., Phonrat, B., Tungtrongchitr, A., Lertrit, P., Tungtrongchitr, R., Kaewsutthi, S., Santiprabhob, J., Phonrat, B., Tungtrongchitr, A., Lertrit, P., and Tungtrongchitr, R., Exome sequencing in Thai patients with familial obesity, vol. 15, p. -, 2016.

Obesity is a major worldwide health issue, with increasing prevalence in adults and children from developed and developing countries. Obesity causes several chronic diseases, including cardiovascular and respiratory diseases, osteoarthritis, hypertension, stroke, type II diabetes, obstructive sleep apnea, and several types of cancer.

Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study

S. Kulanuwat, Santiprabhob, J., Phonrat, B., Limwongse, C., Tungtrongchitr, A., Chongviriyaphan, N., and Tungtrongchitr, R., Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study, vol. 14, pp. 9136-9144, 2015.

Genetic variants of the POMC and PCSK1 genes cause severe obesity among patients in the early stages of childhood. This family-based study analyzed the links between single nucleotide polymorphisms (SNPs) in either the POMC or PCSK1 genes and obesity, as well as obesity-related traits among obese Thai children and their families. The variants rs1042571 and rs6713532 in the POMC gene in a sample of 83 obese children and their family members were investigated using polymerase chain reaction (PCR)-restriction fragment length polymorphism.

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