Body mass index

Relationship between serum creatinine and obesity in children in Xinjiang, China

X. - M. Li, Ma, Y. - T., Xie, X., Yang, Y. - N., Li, X. M., and Zheng, Y. - Y., “Relationship between serum creatinine and obesity in children in Xinjiang, China”, vol. 13, pp. 2409-2416, 2014.

This study was designed to analyze the relationship between serum creatinine and body mass index in children in Xinjiang, China. We used a stratified sampling method to select 5222 children aged 6-17 years in 3 areas in Xinjiang and then measured serum creatinine with an enzymatic method. Our analysis showed that the mean serum creatinine of the various age groups differed, and the reference value increased gradually with age.

Roles of beta2-adrenergic receptor gene polymorphisms in a Turkish population with obstructive sleep apnea syndrome or obesity

İ. Gök, Çelebi, İ., Hüseyinoğlu, N., and Özic, C., “Roles of beta2-adrenergic receptor gene polymorphisms in a Turkish population with obstructive sleep apnea syndrome or obesity”, vol. 13, pp. 8511-8518, 2014.

We determined the distribution of the Arg16Gly and Gln27Glu polymorphisms of the beta-2 adrenergic receptor gene (ADRB2) in patients with obstructive sleep apnea syndrome as well as a control group in Northeastern Turkey. A total of 52 patients diagnosed with obstructive sleep apnea in a sleep laboratory and 78 control subjects were examined. Peripheral blood samples were taken from patients diagnosed with obstructive sleep apnea by polysomnography. DNA was extracted from blood samples and amplified using polymerase chain reaction.

Prevalence and risk factors of overweight and obesity among individuals over 40 years old in Luzhou city

J. Zeng, Wan, Q., Bai, X., Li, X. Z., Liu, F., Li, C., Liu, X. Y., and Wang, Y., “Prevalence and risk factors of overweight and obesity among individuals over 40 years old in Luzhou city”, vol. 13, pp. 9262-9270, 2014.

In this study, a survey was conducted through questionnaire distribution and physical examinations were performed in 10,150 residents that were over 40 years old in Luzhou city. Respondents were selected by the multi-stage sampling method. The mean body mass index (BMI) of the sample population was 23.9 ± 3.3 kg/m2. Among men, BMI showed a negative relationship with increasing age (P

A family-based association study identified CYP17 as a candidate gene for obesity susceptibility in Caucasians

H. Yan, Guo, Y., Yang, T. - L., Zhao, L. - J., and Deng, H. - W., “A family-based association study identified CYP17 as a candidate gene for obesity susceptibility in Caucasians”, vol. 11, pp. 1967-1974, 2012.

The cytochrome P450c17α gene (CYP17) encodes a key biosynthesis enzyme of estrogen, which is critical in regulating adipogenesis and adipocyte development in humans. We therefore hypothesized that CYP17 is a candidate gene for predicting obesity.

Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico

E. Flores-Alfaro, Fernández-Tilapa, G., Salazar-Martínez, E., Cruz, M., Illades-Aguiar, B., and Parra-Rojas, I., “Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico”, vol. 11, pp. 2258-2267, 2012.

Variants in the C-reactive protein (CRP) gene have been found to be associated with various phenotypic traits. We evaluated the effect of four SNPs in the CRP gene on serum levels of protein and body mass index (BMI) in 150 unrelated Mexican subjects from 18 to 25 years old, without hypertension, non-overweight, and without inflammatory diseases, non-smoking and non-consumers of alcohol. Subjects were measured for BMI, waist circumference, blood pressure, and serum glucose and triglycerides. The identification of SNPs was performed by PCR-RFLP.

Association between PPARγ2 Pro12Ala polymorphism and myocardial infarction and obesity in Han Chinese in Hohhot, China

L. P. Wang, Zhao, L. R., Cui, H. W., Yan, M. R., Yang, L., and Su, X. L., “Association between PPARγ2 Pro12Ala polymorphism and myocardial infarction and obesity in Han Chinese in Hohhot, China”, vol. 11, pp. 2929-2938, 2012.

Activation of the peroxisome proliferator-activated receptor g (PPARg) improves insulin sensitivity and inhibits atherosclerosis. Whether PPARg2 Pro12Ala polymorphism affects myocardial infarction is not clearly understood. We investigated a possible association of PPARg2 Pro12Ala polymorphism with obesity and myocardial infarction in Han Chinese in Hohhot, Inner Mongolia, China. We included 121 subjects with myocardial infarction and 137 healthy controls in our study.

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