BMP-2/4

Local expression and role of BMP-2/4 in injured spinal cord

Z. S. Cui, Zhao, P., Jia, C. X., Liu, H. J., Qi, R., Cui, J. W., Cui, J. H., Peng, Q., Lin, B., and Rao, Y. J., Local expression and role of BMP-2/4 in injured spinal cord, vol. 14, pp. 9109-9117, 2015.

We investigated local changes in BMP-2/4 expression in rat spinal cords 1 week following injury to study the damage effects of BMP-2/4 in spinal cord injury (SCI). Sprague Dawley rats (45, 4 months old) were randomized into three groups comprising 15 rats each: a SHAM group, an SCI without noggin group (SCIO), and an SCI with noggin group (SCID). The SCIO and SCID groups were subjected to spinal cord hemisection, and motor activity was assessed using the BBB score.

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